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目的 探讨老年原发性高血压病患者左心室重构与颈动脉粥样硬化间的关系。方法 老年原发性高血压病患者 12 0例 ,依据左心室心肌重量指数分为左心室肥厚 (LVH)组和非左心室肥厚 (NLVH)组 ,并选取 4 0例健康老年人为对照组 ,使用彩色多普勒超声仪检查双侧颈总动脉 (CCA)、颈内动脉 (ICA)、颈外动脉 (ECA)的管腔内径 (D)、内膜中层厚度 (IMT)及左心室各相关参数。结果 原发性高血压病患者颈动脉粥样硬化斑块的检出率显著高于对照组。LVH组和NLVH组患者CCA、ICA、ECA阻力指数均高于对照组 ,LVH组又高于NLVH组。结论 颈动脉粥样硬化的发生与原发性高血压病左心室重构的发生密切相关 ,IMT D值、IMT值是早期诊断颈动脉粥样硬化程度的敏感指标。
Objective To investigate the relationship between left ventricular remodeling and carotid atherosclerosis in elderly patients with essential hypertension. Methods A total of 120 elderly patients with essential hypertension were divided into left ventricular hypertrophy (LVH) group and non-left ventricular hypertrophy (NLVH) group according to left ventricular myocardial mass index. 40 healthy elderly persons were selected as control group. Color Doppler ultrasound examination of bilateral common carotid artery (CCA), internal carotid artery (ICA), external carotid artery (ECA) intraluminal diameter (D), intima-media thickness (IMT) and left ventricular various parameters . Results The detection rate of carotid atherosclerosis in patients with essential hypertension was significantly higher than that in the control group. The resistance index of CCA, ICA and ECA in LVH group and NLVH group were higher than those in control group, while those in LVH group and NLVH group were higher than those in NLVH group. Conclusions The occurrence of carotid atherosclerosis is closely related to the occurrence of left ventricular remodeling in patients with essential hypertension. The IMT D and IMT are the sensitive indicators for the early diagnosis of carotid atherosclerosis.