论文部分内容阅读
目的观察纳洛酮治疗慢性Ⅱ型呼吸衰竭合并肺性脑病的临床疗效。方法将我院2008年11月—2013年11月收治的56例慢性Ⅱ型呼吸衰竭合并肺性脑病病例,随机分为治疗组和对照组,治疗组40例,对照组16例。2组均给以积极有效的治疗,治疗组同时使用纳洛酮治疗,首次以5%葡萄糖液20 mL+盐酸纳洛酮注射液0.8 mg静推后,再持续给予盐酸纳洛酮注射液4 mg加入5%葡萄糖液250 mL静脉点滴,1次/d,14 d为1个疗程。结果治疗组总有效率为92.5%(37/40),对照组总有效率为75%(12/16),治疗组明显高于对照组。治疗过程中未发生不良反应。结论纳洛酮治疗慢性Ⅱ型呼吸衰竭合并肺性脑病有明显的疗效,而且安全。
Objective To observe the clinical efficacy of naloxone in treating chronic type Ⅱ respiratory failure with pulmonary encephalopathy. Methods 56 cases of chronic type Ⅱ respiratory failure with pulmonary encephalopathy admitted from November 2008 to November 2013 in our hospital were randomly divided into treatment group and control group, 40 cases in the treatment group and 16 cases in the control group. Both groups were given an active and effective treatment, the treatment group also used naloxone treatment, the first time to 5% glucose solution 20 mL + naloxone hydrochloride injection 0.8 mg static push, then continue to give naloxone hydrochloride injection 4 mg Add 5% glucose solution 250 mL intravenous drip, 1 time / d, 14 d for a course of treatment. Results The total effective rate was 92.5% (37/40) in the treatment group and 75% (12/16) in the control group, which was significantly higher in the treatment group than in the control group. No adverse reactions occurred during treatment. Conclusion Naloxone treatment of chronic type Ⅱ respiratory failure with pulmonary encephalopathy have a significant effect, but also safe.