目的探究清热解毒种类的中成药的抑制细菌效果,同时研究对于中成药微生物限度检查方法。方法遵照《中华人民共和国药典》2005年版,对微生物的限度检查方法进行有效的实验并验证。结果大肠菌群和大肠埃希菌无抑制活性,可直接在常规法检查中应用。结论有必要建立医院专业的微生物限度检查,采用培养基稀释法,冰醋酸薄膜过滤法进行微生物限度检查。 Objective To investigate the bacteriostatic effect of proprietary Chinese medicines of detoxification and detoxification. At the same time, it is necessary to study the method of checking the limit of microorganisms of proprietary Chinese medicines. Methods According to “The People’s Republic of China Pharmacopoeia” 2005 edition, the limits of microbial detection methods for effective experiments and verification. Results coliforms and Escherichia coli inhibitory activity can be directly used in routine examination. Conclusion It is necessary to establish a hospital professional microbiological limit test, the use of medium dilution method, acetic acid membrane filtration method for microbial limit test.