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目的:探析宫颈癌筛查中TCT及HPV检测的应用效果及可行性。方法:选取我站2013年1月至2015年12月期间接受宫颈癌筛查的500例女性为研究对象,分别给予TCT(液基细胞学检查)、HPV(高危型人类乳头状瘤病毒)检测,以宫颈活检病理学结果为确诊标准,观察比较TCT与HPV检测的应用效果。结果:TCT的特异度为80.0%,灵敏度为52.1%,漏诊率为20.0%,误诊率为47.9%;HPV检测的特异度为73.3%,灵敏度为42.6%,漏诊率为26.7%,误诊率为57.4%,两组比较差异具有统计学意义(P<0.05)。结论:在宫颈癌筛查中,与HPV检测相比,TCT的临床效果更佳,应用价值更高,值得临床选用与推广。
Objective: To explore the application effect and feasibility of TCT and HPV detection in cervical cancer screening. Methods: A total of 500 women who underwent cervical cancer screening from January 2013 to December 2015 in our hospital were enrolled in this study. TCT (liquid-based cytology), HPV (high-risk human papilloma virus) , With cervical biopsy pathology results as the diagnostic criteria, the effect of TCT and HPV testing were observed and compared. Results: The specificity of TCT was 80.0%, the sensitivity was 52.1%, the rate of misdiagnosis was 20.0% and specificity was 47.9%. The specificity of TCT was 73.3%, the sensitivity was 42.6% and the misdiagnosis rate was 26.7% 57.4%, the difference between the two groups was statistically significant (P <0.05). Conclusion: In cervical cancer screening, compared with HPV testing, TCT has better clinical effect and higher application value, which is worthy of clinical application and promotion.