早在三十年代中期德国就已经使用磷化氢作为散装谷物的熏蒸剂(Heseltine 和 Thomp-son,1957),直到五十年代中期磷化铝的试制成功才使之大量应用于生产中(Winks 和Bailey,1965)。Lindgren 等人(1958)最早着手研究和评价磷化氢对于储粮害虫的毒性,但这一评价却主要着重于实际应用上。六十年代(例如 Qureshi 等人,1965;Lindgren和 Vincent)1966;Reynolds等人,1967)才进行详细的实验室分析,但研究的结果也缺 As early as the mid-1930s, Germany had used phosphine as a fumigant for bulk cereals (Heseltine and Thomp-son, 1957), which was not widely used in production until the mid-1950s when trial production of aluminum phosphide was made And Bailey, 1965). Lindgren et al. (1958) were the first to study and evaluate the toxicity of phosphine to stored grain pests, but the evaluation was mainly focused on practical application. A detailed laboratory analysis was conducted in the 1960s (eg, Qureshi et al., 1965; Lindgren and Vincent, 1966; Reynolds et al., 1967), but the results of the study were also lacking