论文部分内容阅读
为探讨肺癌脊柱转移放射治疗的时间剂量分割方法及其疗效 ,将肺癌脊柱转移 6 4例患者随机分为治疗组和对照组 ,治疗组每次 3Gy,每周 5次 ,共 30Gy;对照组每次 2Gy ,每周 5次 ,共 5 0Gy;两组均使用 6mVX线照射。分别比较疼痛缓解率、止痛起效时间、及脊髓压迫缓解率。结果显示治疗组和对照组的疼痛缓解率分别为 87.5 %和 81.3% ,无显著性差异 (P >0 .0 5 ) ;平均止痛起效时间分别为 8± 2 .2天和 15± 3.2天 ,差异性显著 (P <0 .0 1) ;脊髓压迫缓解率分别为 85 .0 %和 81.8% ,无显著性差异 (P >0 .0 5 )。结果表明放射治疗肺癌脊柱转移疗效好 ,起效快 ,建议使用 30Gy/10f/2W的时间剂量分割模式。
In order to explore time-dose-dividing method and efficacy of radiotherapy for spine metastasis of lung cancer, 64 patients with spine metastasis of lung cancer were randomly divided into treatment group and control group. Each treatment group was treated with 3Gy for 5 times a week for 30 Gy. Times 2Gy, 5 times a week, a total of 5Gy; 6mVX line irradiation were used in both groups. Respectively pain relief rate, pain relief onset time, and spinal cord compression remission rate. The results showed that the pain relief rates of the treatment group and the control group were 87.5% and 81.3%, respectively, with no significant difference (P> 0.05); the average pain onset time was 8 ± 2.2 days and 15 ± 3.2 days (P <0.01). The response rate of spinal cord compression was 85.0% and 81.8% respectively, with no significant difference (P> 0.05). The results show that radiotherapy lung spine metastasis good effect, rapid onset, it is recommended to use 30Gy / 10f / 2W time dose segmentation mode.