患者,女,53岁。因乏力,膝、踝关节疼痛,烦渴、多尿1年,间歇性四肢软瘫4个月入院。自1989年3月起双膝、踝关节疼痛,有时晨起关节僵硬,下肢无力,不能走远路及负重,怕冷、脱发、记忆力下降,烦渴、多尿,每日出入水量约3000ml。入院前4个月突发四肢软瘫,无呼吸困难及大小便失禁。住当地医院测血钾2.4mmol/L,诊断为“周期性麻痹。”经静脉及口服氯化钾后恢复了自主运动,但仍觉四肢酸软,行走吃力,此后口服氯化钾3g/d,停药即复发。无水肿、多汗、尿频及血尿史。家中无 Patient, female, 53 years old. Due to fatigue, knee, ankle pain, polydipsia, polyuria 1 year, intermittent limbs soft paralysis 4 months admission. Since March 1989 knees, ankle pain, and sometimes early morning joint stiffness, weakness in the lower limbs, can not go far and weight, cold, hair loss, memory loss, polydipsia, polyuria, daily intake and drainage of about 3000ml. 4 months before admission suddenly flaccid limbs, no breathing difficulties and incontinence. Live in the local hospital serum potassium 2.4mmol / L, diagnosed as “periodic paralysis.” After intravenous and oral potassium chloride to restore the autonomic movement, but still feel limbs sore, difficult to walk, since oral potassium chloride 3g / d, Drug withdrawal is relapse. No edema, sweating, frequent urination and hematuria. No home