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例1.男,3个月,体重4.5kg。患儿因发热、咳嗽20天,呼吸困难7日入院.查体:意识清,嗜睡,营养略差,皮肤弹性差,前囟饱满,左侧眼球外展受限,口唇轻度发绀,颈部轻度抵抗,双肺呼吸音粗糙,未闻及干湿性罗音,心脏未见异常,肝脏肋下3.5cm,质中等度,脾脏肋下20cm,布、克氏征阳性.胸片示两肺广泛粟粒状阴影,右下肺部分融合.脑脊液示典型结脑改变.入院后即给予链霉素、异烟肼、激素、甘露醇等治疗.肝功能回报正常后给予利福平75mg/d口服(仅服1次);服药后14小时即出现皮肤黄染,
Example 1. Male, 3 months, weight 4.5kg. Children with fever, cough 20 days, difficulty breathing on the 7th admission. Physical examination: consciousness clear, drowsiness, slightly poor nutrition, skin elasticity is poor, full of anterior fontanelle, limited left eye abduction, mild lip lips, neck Mild respiration, rough lung breath sounds, no smell and wet and dry rales, the heart no abnormal liver subglottic 3.5cm, moderate quality, spleen ribs 20cm, cloth, Kirschner sign positive. Pulmonary miliary shadow of the broad, right lower lung part of the fusion cerebrospinal fluid showed typical changes in the brain .After admission to give streptomycin, isoniazid, hormone, mannitol and other liver function returned to normal after given rifampicin 75mg / d Oral (serving only 1); 14 hours after taking the skin yellow dye,