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目的下肢恶性黑色素瘤手术的腹股沟淋巴结清扫范围一直是人们争论的焦点。本研究旨在探讨腹股沟淋巴结清扫范围对下肢恶性黑色素瘤预后的影响。方法共收集34例病例,分为两组,18例仅行浅表淋巴结清扫术(Superficial inguinal lymphadenectomy,SLND),16例联合行髂窝淋巴结清扫术(Combined inguinal lymphadenectomy,CLND),对其进行回顾性分析。结果SLND组与CLND组比较,一般资料无统计学差异,总生存期为46.8 vs 45.1(月,P=0.272);无病生存期为36.1 vs 35.9(月,P=0.719);术后住院天数为16.5 vs 23.0(天,P=0.066);并发症发生率为38.9 vs 75.0(%,P=0.045)。结论对于髂窝淋巴结临床阴性的下肢恶性黑色素瘤,仅行浅表淋巴结清扫是可行的。
The purpose of the lower extremity malignant melanoma surgery inguinal lymph node dissection range has been the focus of controversy. The purpose of this study was to investigate the effect of dissection of inguinal lymph nodes on the prognosis of malignant melanoma in the lower extremities. Methods A total of 34 cases were collected and divided into two groups. Eighteen patients underwent superficial inguinal lymphadenectomy (SLND) and 16 patients underwent combined inguinal lymphadenectomy (CLND) Sexual analysis. Results The overall survival was 46.8 vs 45.1 (month, P = 0.272); the disease-free survival was 36.1 vs 35.9 (month, P = 0.719); the number of postoperative hospital stays Was 16.5 vs 23.0 (days, P = 0.066). The complication rate was 38.9 vs 75.0 (%, P = 0.045). Conclusions Only superficial lymph nodes dissection is feasible for malignant melanoma of lower extremity clinically negative in the iliac lymph nodes.