急性胃粘膜病变、消化性溃疡是临床上的常见病、多发病，其发病机理一般认为是攻击因子与胃粘膜防御机制动态失衡所致、既往，对其的研究多侧重于前者，治疗强调清除攻击因子，临床疗效往往不佳。新近认为，这些疾病均与胃粘膜防御机制的某环节或多环节受破坏有关。因此，如何 Acute gastric mucosal lesions and peptic ulcers are common clinical and frequently-occurring diseases. The pathogenesis is generally believed to be caused by the dynamic imbalance between the attacking factors and the gastric mucosal defense mechanisms. Its research focuses more on the former and the treatment emphasizes the elimination. Attack factor, clinical efficacy is often poor. Recently, it is believed that these diseases are related to the destruction of a certain link or multiple aspects of the gastric mucosal defense mechanism. So how