论文部分内容阅读
《新英格兰医学杂志》(New England Journal of Medicine)在2012年5月17日发表了一项关于华法林和阿司匹林在治疗射血分数(LVEF)降低患者疗效比较研究(WARCEF)的结果。该项研究表明:对于窦性节律LVEF降低的患者,使用华法林治疗还是阿司匹林治疗,主要终点事件没有总体上的差异。华法林降低缺血性卒中风险的获益被其严重出血风险的增加所抵消。因此,选择华法林还是阿司匹林治疗要因人而异(N Engl J Med,2012,366:1859-1869)。
On May 17, 2012, the New England Journal of Medicine published a report on the comparative efficacy of warfarin and aspirin in reducing the ejection fraction (LVEF) in patients treated with warfarin (WARCEF). This study shows that there is no overall difference in the primary endpoint of treatment with warfarin or aspirin in patients with reduced sinus rhythm LVEF. The benefit of warfarin in reducing the risk of ischemic stroke was offset by an increase in the risk of severe bleeding. Therefore, the choice of warfarin or aspirin treatment varies from person to person (N Engl J Med, 2012, 366: 1859-1869).