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近年来发现经羟氨喹反复治疗的病人中分离出的曼氏血吸虫株对羟氨喹已产生抗性,而对吡喹酮敏感;因此作者对吡喹酮作为治疗晚期肝脾型血吸虫病的替代药物进行了评价。作者用吡喹酮治疗15名10～55岁男性埃及人。治疗对象的选择标准是脾在肋缘下超过5cm,2次曼氏血吸虫虫卵计数的平均数≥100个/g粪便。除1例肝萎缩外,所有
In recent years, it has been found that the Schistosoma mansoni isolated from patients who have been repeatedly treated with hydroxyquinate have already developed resistance to hydroxyquinc and are sensitive to praziquantel. Therefore, the authors of this article consider praziquantel as the treatment of advanced hepatosplenic schistosomiasis Alternative medicine was evaluated. The authors used praziquantel treatment of 15 male Egyptians 10 to 55 years old. The selection criteria for treatment were spleens over 5 cm below the costal margin and an average of two egg counts of Schistosoma mansoni ≥ 100 / g faeces. In addition to 1 case of liver atrophy, all