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目的探讨血清同型半胱氨酸(Hcy)和超敏C反应蛋白(hs-CRP)的检测在原发性高血压病中的临床价值。方法对59例原发性高血压患者和30例健康体检者进行血清Hcy和hs-CRP的检测并进行比较。结果原发性高血压患者血清Hcy和hs-CRP的水平均明显高于正常对照组(P均<0.01),且男性高于女性(P<0.05或P<0.01)。结论血清Hcy和hs-CRP是原发性高血压发病的重要危险因素,其检测对高血压病的预防、诊断及治疗有重要的临床意义。
Objective To investigate the clinical value of detecting serum homocysteine (Hcy) and high sensitivity C-reactive protein (hs-CRP) in patients with essential hypertension. Methods Serum Hcy and hs-CRP levels in 59 patients with essential hypertension and 30 healthy subjects were measured and compared. Results The levels of serum Hcy and hs-CRP in patients with essential hypertension were significantly higher than those in controls (all P <0.01), and were higher in males than in females (P <0.05 or P <0.01). Conclusions Serum Hcy and hs-CRP are important risk factors for the pathogenesis of essential hypertension. The detection of Hcy and hs-CRP is of great clinical significance in the prevention, diagnosis and treatment of hypertension.