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目的：探讨恶性肿瘤时高凝状态的发病机制。方法：对贲门癌患者手术前后血小板数目、血小板聚集性、凝血因子活性进行了观察，并且施以氧自由基清除剂茶多酚，观察其对上述各指标的影响。结果：贲门癌患者血小板聚集率增高，聚集时间延长；凝血因子活性增加；与同期不服药组相比，术后服药组上述各项指标均有明显改善。结论：氧自由基在贲门癌患者高凝状态的形成中起着重要的作用，清除氧自由基可以减少并发症，延长病人的生存期。
Objective: To investigate the pathogenesis of hypercoagulability in malignant tumors. Methods: The platelet count, platelet aggregation, and coagulation factor activity were observed before and after surgery in patients with cardiac cancer. The oxygen free radical scavenger tea polyphenols was applied to observe the effects of the above indicators. RESULTS: The platelet aggregation rate of patients with cardiac cancer increased, the time of aggregation prolonged, and the activity of coagulation factors increased. Compared with the non-drug group in the same period, the above-mentioned indexes in the post-administration group were significantly improved. Conclusion: Oxygen free radicals play an important role in the formation of hypercoagulable state in patients with cardiac cancer. The removal of oxygen free radicals can reduce complications and prolong the survival of patients.