【摘 要】
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A method of high performance liquid chromatographic separation of clausenamide enantiomers with chiral-AGP(α1-acid glycoprotein)stationary phases has been esta
【机 构】
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Institute of Materia Medica
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A method of high performance liquid chromatographic separation of clausenamide enantiomers with chiral-AGP(α1-acid glycoprotein)stationary phases has been established.The absolute configurations of(-)clausenamide and(+)clausenamide are 3S,4R,5R,6S and 3R,4S,5S,6R,respectively.The present method has been used to analyze the(-)clausenamide and(+)clausenamide and its analogues such as the major metabolite and synthetic derivatives of clansenamide.
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