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节细胞性神经母细胞瘤罕见,而发生于中耳者世界医学文献尚未见报道,本文报道1例,为一3岁女孩,右耳流脓并伴有面神经瘫。手术见肿瘤侵犯破坏右乳突腔及外耳道骨壁。病理组织学检查发现肿瘤由类似神经节细胞及神经母细胞的二类瘤细胞所组成,并有形态介于上述二类细胞之间的过渡型细胞。有菊形团形成趋向,镀银染色显示瘤细胞之间有神经原纤维存在。对节细胞性神经母细胞瘤的形态特征,病理诊断标准以及生物学行为作了简要文献复习和讨论。
Cell-borne neuroblastoma rare, but in the middle ear in the world of medical literature has not been reported, this article reported 1 case, a 3-year-old girl, right ear pus accompanied by facial paralysis. Surgery to see violations of the right breast tumor destruction and external auditory canal wall. Histopathological examination revealed that the tumor consisted of two types of tumor cells similar to ganglion cells and neuroblasts, and had transitional cells in morphology between the above two types of cells. There are chrysanthemum formation trend, silver staining shows the presence of neurofibrils between tumor cells. On the section of cell neuroblastoma morphological features, pathological diagnostic criteria and biological behavior made a brief review and discussion of the literature.