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人诱导性多能干(iPS)细胞能够分化成很多种类的祖细胞,这为临床和研究提供了新的机遇。这些细胞系可以用于疾病模型的建立、药物筛选以及毒性测试、帮助解决传统方法的局限性,也可以建立人类各种复杂疾病的细胞模型,对应用于更加个性化的医药研究领域也很有潜力。这些细胞系具有重新塑造临床研究领域的潜力,但是研究人员也面临着很多问题和挑战,也需要去发现新的应用。
Human induced pluripotent stem (iPS) cells can differentiate into many kinds of progenitor cells, which provide new opportunities for clinical and research. These cell lines can be used for the establishment of disease models, drug screening and toxicity testing to help address the limitations of traditional methods as well as to establish cellular models of various complex human diseases, as well as for the more personalized medical research potential. These cell lines have the potential to reshape clinical research, but researchers face many problems and challenges as well as discover new applications.