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骨显像是临床有价值的核医学检查项目。HMDP(Hydroxymethylene Diphosphonate)是最近发现的一种较好的二膦酸盐类骨显像剂。 我室与核药学研究室联合研制成功了HMDP药盒,并在大白鼠体内做了~(99m)Tc-HMDP、~(99b)Tc-MDP、~(99)Tc-PYP分布比较,在家兔体内做了~(99m)Tc-HMDP、~(99m)Tc-MDP血清除率、尿排泄率、显像质量的自身对照。
Bone imaging is a clinically valuable nuclear medicine test. HMDP (Hydroxymethylene Diphosphonate) is a recently found a good bisphosphonate bone imaging agent. HMDP kit was successfully developed in our laboratory and the Nuclear Pharmacy Laboratory. Compared with 99m Tc-HMDP, 99b Tc-MDP and 99 Tc-PYP distribution in rats Rabbits made ~ (99m) Tc-HMDP, ~ (99m) Tc-MDP serum clearance rate, urinary excretion rate, imaging quality self-control.