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该药为淡黄色结晶或结晶性粉末,无臭,味苦,不溶于水,易溶于热酒精、苯、氯仿、丙酮等有机溶媒中。本品为第十六届国际消化会议推荐的优良抗溃疡新药,对消化性溃疡的治愈率接近甲氧咪胍。1978年意大利已有商品上市,国内由河南省医药工业研究所研制成功,已于1981年12月通过鉴定。经药理试验表明,它具有抗胃液分泌的活性,对消化性溃疡所引起的疼痛有效。对不同的实验动物模删口服本品25~100mg/kg,具有良好的抗胃液分泌和
The drug is light yellow crystalline or crystalline powder, odorless, bitter, insoluble in water, soluble in hot alcohol, benzene, chloroform, acetone and other organic solvents. This product is recommended for the 16th International Digestion Conference excellent anti-ulcer drug, the cure rate of peptic ulcer close to the methoxy-guanidine. 1978 Italy has been listed on the market, the domestic pharmaceutical industry by the Institute of Henan Province successfully developed, in December 1981 passed the appraisal. Pharmacological tests show that it has anti-gastric secretion activity, the pain caused by peptic ulcer effective. For different experimental animal model oral administration of this product 25 ~ 100mg / kg, has a good anti-gastric secretion and