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目的 探讨肝动脉化疗栓塞 (TAE)对原发性肝癌的疗效 ,并对严重并发症原因予以分析。方法选择原发性肝癌 3 96例 ,60 5次介入 ,观察疗效 ,记录并发症。结果 总体 1、2、3、4、5a生存率分别是 4 5 4 %、4 2 1%、19 2 %、2 3 %、1 3 % ,最长 1例存活 8a 3个月 ;严重并发症发生 2 1例 ,发生率为 5 3 % ,死亡 17例 ,病死率 81% ( 17/ 2 1) ;3 2例经TAE后行了Ⅱ期切除术 ;4 0例右肝巨大肝癌有异常血供。结论 TAE是中晚期肝癌有效的治疗方法 ;使部分病人可行Ⅱ期切除 ;但在行介入时应严格掌握指征 ,减少严重并发症发生 ,一旦发生 ,其病死率高 ,应引起高度重视 ;发现肿瘤异常血供并予以栓塞是提高疗效的措施之一。
Objective To investigate the effect of hepatic arterial chemoembolization (TAE) on primary liver cancer and analyze the causes of serious complications. Methods A total of 3 96 cases of primary liver cancer were selected and 60 5 interventions were performed to observe the curative effect and record the complications. Results The overall 1, 2, 3, 4 and 5 a survival rates were 454, 41.2%, 192%, 25%, and 15%, respectively. The longest one survived 8a and 3 months; serious complications were observed. There were 21 cases, the incidence was 53%, 17 cases died, and the mortality was 81% (17/21). Thirty-two cases had undergone phase II resection after TAE; 40 cases had abnormal hepatocellular carcinoma with abnormal blood for. Conclusions TAE is an effective treatment for advanced hepatocellular carcinoma, and it can be used to treat some patients with stage II resection. However, the indications should be strictly controlled during the intervention to reduce serious complications. Once it occurs, the mortality is high, and it should be highly valued; Abnormal blood supply to the tumor and embolization is one of the measures to improve the curative effect.