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脑回异常以皮质结构的严重紊乱为特征,包括在深部表面沟回数目的减少,沟回的完全缺乏称为“无脑回”,脑回减少称为“巨脑回”,小的脑回增多称为“多小脑回”。从神经病理的角度出发,可分为几种组织学类型。作者对MRI或CT轴状扫描诊断为广泛性脑回畸形的43例病人,根据其影像学特征进行分类,对不同类型间的临床、EEG和基因特征进行对比性研究。选择下列放射学标准作为确诊依据:(1)每侧半球至少二叶皮质区的沟回缺乏或减少;(2)灰、白质间的交叉缺乏或减少。
Abnormal gyration of the brain is characterized by severe disorders of the cortical structure, including a decrease in the number of furrows in the deep surface, a complete absence of furrows called “no brain back”, a decrease in brain back called “giant brain back”, a small gyrus gyrus Known as the “multiple cerebellum back.” From the neuropathological point of view, can be divided into several types of histology. The authors categorized 43 patients with extensive brain deformity diagnosed by MRI or CT axial scans and compared the clinical, EEG and genetic characteristics of different types according to their imaging features. The following radiological criteria were selected as the basis for diagnosis: (1) lack or decrease of ditch in at least two cortex regions on each hemisphere; and (2) lack or decrease of crossover between gray and white matter.