甲异靛治疗慢性粒细胞白血病（ＣＭＬ）已有了近２０年的历史，该药对ＣＭＬ近期有效率为９０．１％［１］。我所自１９９４年４月～１９９５年４月对１８例ＣＭＬ患者应用甲异靛（部分联合干扰素）治疗，随访观察至１９９９年６月，总结如下。１　资料与方法１．１　病例选择 The treatment of chronic myelogenous leukemia (CML) with methotrexate has been in the past 20 years. The effective rate of this drug for CML is 90.1% [1]. Since April 1994-April 1995, our institute has used 18 cases of CML patients to be treated with methotrexate (partial combined interferon). Follow-up observation until June 1999 was summarized as follows. 1 Materials and Methods 1.1 Case Selection