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目的探讨老年人急性心肌梗死（心梗）卡托普利治疗对预后的意义。方法６３１例首次急性心梗后７２小时内入院无心源性休克老年患者中，３６１例早期及随访期持续卡托普利治疗（治疗组），２７０例常规治疗（对照组），比较两组住院期和随访期生存率的差异。结果住院期治疗组生存率（９２．２％）显著高于对照组（７８．９％，Ｐ＜０．００１），卡托普利对前壁心梗作用较下壁心梗明显。随访期（第９周～第５４个月末）第５４个月末治疗组累积生存率（９１．０％）显著高于对照组（７４．０％，Ｐ＜０．０１），心源性事件累积发生率（５５．０％）低于对照组（７２．０％，Ｐ＜０．０００１）。结论老年人急性心梗后早期及持续卡托普利治疗对其预后具有益作用
Objective To investigate the significance of captopril in elderly patients with acute myocardial infarction (MI) on prognosis. Methods Among 631 elderly patients without cardiogenic shock admitted within 72 hours after the first acute myocardial infarction, 361 patients were treated with captopril in the early and follow-up periods (treatment group) and 270 patients in the routine treatment group (control group) Differences in survival between follow-up and follow-up periods. Results The survival rate of hospitalized patients was significantly higher than that of the control group (92.2%) (78.9%, P <0.001). The effect of captopril on the anterior myocardial infarction was significantly lower than that of the inferior wall. At the end of the 54th month, the cumulative survival rate (91.0%) in the treatment group was significantly higher than that in the control group (74.0%, P <0.01). The cumulative incidence of cardiac events The incidence (55.0%) was lower than that in the control group (72.0%, P <0.0001). Conclusion The early and persistent captopril treatment in elderly patients has a beneficial effect on the prognosis