随着抗菌素的发展和普及,出现了耐药菌株、过敏、顽固的感染,以及应用广谱抗菌素引起的二重感染等问题。因此,必须同时顾及宿主机体方面的因素。抗菌素虽能抑制或杀灭入侵的病原体,但对病原体的菌体成分、毒素和代谢产物等引起的炎症反应,则无任何直接影响。虽然炎症系机体对感染的防御反应,但如过于严重,则增加病人的负担和痛苦,甚至可以致命。 With the development and popularization of antibiotics, there have been many problems such as drug-resistant strains, allergies, stubborn infections and double infections caused by the use of broad-spectrum antibiotics. Therefore, it must take into account the host body factors. Although antibiotics can inhibit or kill invading pathogens, they have no direct effect on the inflammatory response caused by the bacterial constituents, toxins and metabolites of pathogens. Although inflammation is the body’s defense response to infection, if it is too serious, the burden and suffering of the patient are increased and can even be fatal.