严重鼻溢常影响患者的生活质量，带来诸多不便。为减轻鼻溢的痛苦，患者不得不鼻内或全身使用拟交感神经药、色甘酸钠和类固醇制剂，或选择性地全身使用抗组胺药，或特异性免疫治疗，但每类药物各有其优缺点。早在１００年前硫酸阿托品就被用于治疗急性鼻炎和过敏性鼻炎的鼻溢 Serious rhinorrhea often affect the quality of life of patients, bringing a lot of inconvenience. In order to alleviate the pain of rhinorrhea, patients have to intranasally or systemically use sympathomimetic drugs, cromolyn and steroid formulations, or systemic systemic antihistamines or specific immunotherapy, but each has its own Its advantages and disadvantages. As early as 100 years ago, atropine sulfate was used to treat rhinitis of acute rhinitis and allergic rhinitis