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目的了解辽阳市HIV抗体筛查、确证检测情况,为辽阳市艾滋病预防检测工作提供更合理的指导依据。方法收集2011—2013年辽阳市HIV筛查阳性样本,采用蛋白印迹(WB)法进行检测,c2统计分析。结果辽阳市2011—2013年128份HIV抗体筛查阳性的样本,WB确证85份为阳性,阳性率为66.41%;15份为不确定,占11.72%;28份为阴性,占21.88%。3者间S/CO分布差异有统计学意义(χ2=111.794,P<0.05)。且S/CO值>6时与确证阳性符合率达95.3%(81/85),确证阳性出现全带型为42份,占49.4%。结论 HIV抗体筛查实验存在一定数量的假阳性,即使S/CO值>6时也不能完全代替确证实验。不确定样本,随访同时须结合流行病学资料及P24抗原、病毒载量检测结果以便做出正确判断。
Objective To understand HIV antibody screening and confirmatory test in Liaoyang City and provide a more reasonable basis for AIDS prevention and detection in Liaoyang City. Methods Positive HIV screening samples from 2011 to 2013 in Liaoyang were collected and detected by WB method and c2 statistical analysis. Results A total of 128 HIV antibody positive samples were detected in Liaoyang from 2011 to 2013, 85 of which were confirmed positive by WB. The positive rate was 66.41%, 15 were uncertain, accounting for 11.72%, and 28 were negative, accounting for 21.88%. There were significant differences in S / CO distribution between the three groups (χ2 = 111.794, P <0.05). And the positive coincidence rate with confirmed positive was 95.3% (81/85) when S / CO value was> 6, and 42 cases were confirmed positive, accounting for 49.4%. Conclusion There is a certain amount of false positives in the HIV antibody screening test, which can not completely replace the confirmation test even if the S / CO value is> 6. Uncertain samples, follow-up should be combined with epidemiological data and P24 antigen, viral load test results in order to make the right judgments.