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目的:探讨影响保乳手术成功的相关性因素。方法:选取我院自2009年12月~2012年12月行保乳手术切缘阳性32例患者与同期切缘阴性且保乳成功35例患者的进行比较分析,观察影响手术中的切缘状态,并对影响手术成功的相关性因素进行分析观察。结果:通过单因素分析可发现,手术术式、微钙化范围、广泛导管内癌成分(EIC)、组织学分级是影响手术成功的相关性因素;多因素分析下,手术术式、EIC、组织学分级及微钙化范围是影响保乳手术成功的因素。结论:术中切缘是够呈阳性是影响保乳手术成功的决定性因素,而首次切缘重度不典型增生、同侧腋下淋巴结转移数目及EIC是保乳手术成功与否的重要因素。
Objective: To explore the factors influencing the success of breast-conserving surgery. Methods: From December 2009 to December 2012 in our hospital, 42 patients with positive margins of breast-conserving surgery were compared with 35 patients with negative margins and successful breast-conserving surgery in the same period. The effects of surgical margins , And related factors that affect the success of surgery were analyzed and observed. Results: According to univariate analysis, surgical operation, microcalcification range, extensive intraductal carcinoma (EIC) and histological grade were the related factors influencing the success of surgery. According to multivariate analysis, surgical operation, EIC, The grade of study and the range of micro-calcifications are the factors affecting the success of breast-conserving surgery. CONCLUSION: The positive surgical margins are the decisive factor influencing the success of breast-conserving surgery. However, the incidence of severe atypical hyperplasia, ipsilateral axillary lymph node metastasis and EIC are the important factors in success of breast-conserving surgery.