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FAB协作组最近提出了鉴别慢性粒细胞白血病CGL、慢性粒-单细胞白血病(CMML)和不典型慢性髓系白血病(aCML)的标准。虽然,一般认为(CGL)是一种独立的疾病,但CMML和aCML是独立的疾病还是属于有病态造血特征的骨髓增殖性疾患尚有争论。作者分析了10例就诊时诊断为难治性贫血(RA)的患者,在病程中出现了aCML的临床特点。 10例患者中男5例,女5例;年龄56～86岁。就诊时所有病例均为RA,3例有红细胞再生障碍,白细胞计数1.5～12.2×10~9/L,无1例单核细胞超过1.0×10~9/L。在白细胞增高最多时,所有患者都有明显的粒
The FAB Collaboration recently proposed criteria for the identification of chronic myeloid leukemia CGL, chronic myelomonocytic leukemia (CMML) and atypical chronic myeloid leukemia (aCML). Although (CGL) is generally considered to be an independent disease, it is debated whether CMML and aCML are independent diseases or belong to myeloproliferative disorders characterized by pathological hematopoiesis. The authors analyzed 10 patients diagnosed as refractory anemia (RA) at the time of their visit and showed clinical features of aCML during the course of the disease. There were 5 males and 5 females in 10 cases, ranging in age from 56 to 86 years. All cases were RA, 3 had erythrocyte aplasia, white blood cell count was 1.5-12.2 × 10-9 / L, and none of the cases had more than 1.0 × 10-9 / L monocytes. In patients with the highest increase in white blood cells, all patients have obvious grain