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目的：探讨中心静脉置管导丝锚入尿管内用于非外伤性困难尿管置入的临床价值。方法回顾性分析自2014年1月~2014年12月咸阳市第一人民医院综合ICU 77例非外伤性困难尿管置入患者，随机纳入尿管组及及导丝+尿管组。尿管组39例实施常规导尿。导丝+尿管组38例，予中心静脉置管导丝锚入尿管内导尿，对两组成功率、操作时间、操作过程中面部表情疼痛评分进行比较。结果尿管组39例患者导尿成功率2.56%，操作时间（59.00±6.25）s，疼痛分值（6.79±1.45）分。导丝+尿管组38例患者，成功率97.37%，操作时间（2.87±0.88）s，疼痛分值（3.64±0.99）分。导丝+尿管组较尿管组成功率提高，差异有统计学意义（P＜0.01）。导丝+尿管组较对照组操作时间及疼痛分值下降，差异有统计学意义（P＜0.05，P＜0.01）。结论中心静脉导管导丝锚入尿管内实施导尿术，是非外伤性困难尿管置入的有效应急方案。该方法具有安全、方便，易于操作、成功率高，操作时间短，患者痛苦小、并发症少，非专科医务人员亦能快速掌握等特点，值得临床推广应用。“,”Obective To explore the practicality and superiority of anchoring guidewire used in central venous catheter into urinary catheter lumen for nontraumatic difficult urethral catheterization. Methods Seventy-seven patients were enrolled between Jan.1 2014 and Dec.31 2014 who Failed conventional urethral catheterization in general ICU.Using conventional urethral catheterization in the ureter group, Anchoring guidewire into urinary catheter lumen in guidewire+ureter group. Comparing success rate, running time,Face Pain Rating Scale (FPRS) in two groups. Results Urethral catheterization success rate in guidewire+ureter group were obviously superior to the control group, the difference was statistically significant (P<0.01). Urethral catheterization running time,FPRS was lower than the control group, the two group difference has statistics significance(P<0.05; P<0.01). Conclusions The method of anchoring guidewire used in central venous catheter into urinary catheter lumen for nontraumatic difficult urethral catheterization has certain effects and fewer side effects. So it is worthy of further clinical application.