论文部分内容阅读
目的：研究肠康胶囊的抑菌、行气、镇痛作用。方法：以肠康片作对照，体外抑菌试验用液体试管法，其余均用小鼠灌胃法，给１．０４、０．５２、０．２６ ３ 种不同剂量。结果：肠康胶囊对大肠埃希氏菌等４ 种肠道致病菌均有不同程度的抑制作用， 能对抗苦寒药大黄的致泻作用， 对新斯的明引起的小鼠推进运动亢进有明显的抑制作用，并具有明显的镇痛作用。结论：肠康胶囊的药理作用与肠康片相当甚至强于肠康片，为中药剂型的改进及临床验证提供了实验依据。
Objective: To study the antibacterial, qi and analgesic effects of Changkang Capsule. METHODS: The control group of Changkang Tablet was used as a control. The in vitro antibacterial test was performed by liquid tube method. The rest were all administered with mice by gavage, giving different doses of 1.04, 0.52, and 0.26. RESULTS: The Gakang capsule had inhibitory effects on 4 kinds of enteropathogenic bacteria such as Escherichia coli to varying degrees, and it was able to counteract the diarrhea of bitter cold drug Rhubarb. The mice that had been promoted by neostigmine had hyperthyroidism. Obvious inhibitory effect and obvious analgesic effect. Conclusion: The pharmacological effects of Gengkang Capsule is comparable to that of Changkang Tablet and even stronger than that of Changkang Tablet, which provides experimental basis for the improvement and clinical validation of the Chinese medicinal formula.