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目的了解入伍新兵呼吸道合胞病毒(RSV)IgG抗体水平,为预防RSV感染提供科学依据。方法采用血清流行病学调查方法,利用酶联免疫吸附试验(ELISA),对随机抽取的2001～2008年364名入伍新兵血清进行RSVIgG抗体检测,并进行统计分析。结果 364名新兵血清RSV抗体阳性57人,阳性率15.66%;2001～2008年各年度阳性率6.52%～28.89%,差异有统计学意义(χ2=21.006,P<0.05);被调查新兵来自16个省市,其中天津(47.83%)、广西(39.13%)、山东(34.78%)和甘肃(21.74%)来源新兵RSV抗体阳性率较高,其余省市相对较低,差异有统计学意义(χ2=72.323,P<0.05);入伍前工作与否者抗体阳性率差异无统计学意义(χ2=0.170,P>0.05)。结论入伍新兵RSV抗体水平较低,且存在显著的地区和年度差异,应引起高度重视。
Objective To understand the level of RSV IgG antibody in new recruits and provide a scientific basis for prevention of RSV infection. Methods The serological epidemiological survey method was used to detect the RSV IgG antibody of 364 recruit recruits from 2001 to 2008 by enzyme-linked immunosorbent assay (ELISA), and statistical analysis was performed. Results The seroprevalence of RSV antibodies in 364 recruits was 57, with a positive rate of 15.66%. The positive rates were 6.52% -28.89% in all years from 2001 to 2008, with significant difference (χ2 = 21.006, P <0.05) (47.83%), Guangxi (39.13%), Shandong (34.78%) and Gansu (21.74%). The RSV antibody positive rate among the recruits was relatively high in other provinces and cities, the difference was statistically significant ( χ2 = 72.323, P <0.05). There was no significant difference in the positive rates of antibodies before working or before entering the army (χ2 = 0.170, P> 0.05). Conclusion The level of RSV antibodies in recruits is low, and there are significant regional and annual differences, which should be paid great attention.