[目的]探讨重度颅脑损伤合并闭合性胸部创伤患者的临床急救措施。[方法]我院于2008年2月～2009年7月充分利用医院急救绿色通道与抢救监护设备,改进救治策略,抢救重度颅脑损伤合并闭合性胸部创伤患者75例。[结果]本组75例患者中存活51例(其中可以正常工作及生活者37例,生活仅能自理者9例,长期卧床及植物生存者5例),死亡24例,其中死于ARDS5例,死于休克6例,死于肺内感染8例,死于继发性脑疝4例,死于原发脑干损伤1例。[结论]早期诊断对于重度颅脑损伤合并闭合性胸部创伤患者的临床急救起着至关重要的作用,而在临床急救时,应以保持有效呼吸、迅速补足血容量、解除脑受压为中心环节。这就要求临床医生必须在迅速、全面查体后作出正确判断,并分清主次,对威胁生命的损伤优先处理,必要时多处损伤同时处理,以减少治疗不当造成无法挽回的损失。 [Objective] To investigate the clinical emergency measures for patients with severe craniocerebral injury complicated with closed chest trauma. [Methods] From February 2008 to July 2009, our hospital made full use of hospital emergency greenway and rescue monitoring equipment to improve the treatment strategy and rescue 75 cases of severe traumatic brain injury combined with closed chest trauma. [Results] Totally 51 patients survived in 75 patients (among them, 37 were able to work and live, 9 were able to take care of themselves, and 5 were bedridden and plant survivors). 24 died, of whom 5 died of ARDS , 6 died of shock, 8 died of pulmonary infection, 4 died of secondary hernia and 1 died of primary brain stem injury. [Conclusion] Early diagnosis plays a crucial role in the clinical emergency treatment of patients with severe craniocerebral injury complicated with closed chest trauma. However, in clinical first aid, it is imperative to maintain effective breathing, rapidly increase blood volume and relieve brain compression Links. This requires clinicians must make prompt and comprehensive physical examination to make the correct judgments, and distinguish between primary and secondary, life-threatening injuries priority treatment, if necessary, multiple injuries at the same time to reduce the treatment of irreparable damage.