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急性巨核细胞型白血病的特征是某些器官内具有不典型的和低分化的巨核细胞系统浸润和增生。作者首次观察到1例白血病前期症候群后发展为急性巨核细胞型白血病。患者52岁,男性。因前额部头痛于1975年2月21日住院。追问家族史有二个表兄曾患白血病和一个兄弟患真性红细胞增多症。肝脏上下径14厘米,脾肋下刚触及。两下肢前缘有红斑。血细胞容积27%,外周血见异形红细胞、正色素和低色素与红细胞。白细胞计数和分类正常。血清铁180微克%,血清总铁结合力315微克%,血清叶酸23毫微克/毫升(正常3～16),血清Vit B_(12)
Acute megakaryocytic leukemia is characterized by systemic infiltration and hyperplasia of atypical and poorly differentiated megakaryocytes within certain organs. The authors first observed a leukemic syndrome developed after the first acute megakaryocyte leukemia. Patient 52 years old, male. Headache due to forehead in February 21, 1975 hospitalization. Asked the family history of two cousins had leukemia and a brother suffering from polycythemia vera. Upper and lower liver diameter 14 cm, spleen rib just touched. Both limbs have erythema on the leading edge. 27% of the hematocrit, peripheral blood see shaped red blood cells, n-type pigment and hypochromic and red blood cells. White blood cell count and normal classification. Serum iron 180 μg%, serum total iron binding 315 μg%, serum folic acid 23 ng / ml (normal 3 ~ 16), serum Vit B_ (12)