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在脑缺血及再灌注的动物模型上，利用ＦＬＮａ示踪剂研究软脑膜微血管的通透性，通过测定血液、脑与其它５种脏器的荧光强度及对脑微血管荧光图像初步分析与处理，探讨其内在规律．结果表明，缺血与缺血后再灌注可以引起脑微血管内皮细胞损伤，血液再灌注到一定时间，对损伤有一定的修复；同等条件下，各脏器受损程度不同，其中肝、肾的微血管内皮细胞损伤最重，肺、心次之，脑与脾最轻，即脑、脾微血管抗损能力较强；同时，不同脏器中ＦＬＮａ浓度随时间的衰减规律各不相同，且比较复杂．
In the animal model of cerebral ischemia and reperfusion, FLNa tracer was used to study the permeability of pia mater microvessels. The fluorescence intensity of blood, brain and other 5 kinds of organs was analyzed and the fluorescence image of brain microvessels was analyzed and treated , Explore its inherent laws. The results showed that ischemia and reperfusion can cause brain microvascular endothelial cell injury, blood reperfusion for a certain period of time, to repair the damage; under the same conditions, the degree of damage of various organs, including liver, kidney Microvascular endothelial cell injury is the most serious, lung, heart and heart, brain and spleen lightest, that brain, spleen microvascular anti-damage ability; the same time, FLNa concentrations in different organs decay law over time vary, and more complicated .