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氯卡胺(Lorcainide)有局麻作用和抗心律失常作用。口服后心肌内的血药浓度比血浆中的高,半衰期9～10h。氯卡胺可用于防治各种类型的室性早搏和快速室性心律失常,特别是用于常规治疗药无效的病例。口服首剂以100mg,2次/日为宜,以后可增为150mg,2次/日。副作用有失眠等睡眠紊乱现象,在继续服药中可减轻或消失,对有房室结或房室内传导障碍者慎用。
Lorcainide has local anesthetic effects and anti-arrhythmic effects. After oral administration of plasma concentration of plasma higher than in plasma, half-life of 9 ~ 10h. Chloramaryctin can be used for the prevention and treatment of various types of premature ventricular contractions and rapid ventricular arrhythmias, especially for routine treatment of ineffective cases of drugs. Oral first dose of 100mg, 2 times / day is appropriate, later increased to 150mg, 2 times / day. Side effects such as sleep disorders such as insomnia phenomenon, continue to medication can be reduced or disappeared, with atrioventricular node or room conduction caution.