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在两个边远的阿拉斯加村庄,经流行病学和血清学调查,乙型肝炎病毒(HBV)的感染率高达55%。成年人中具有对乙型肝炎表面抗原(HBsAg)的抗体者高达55%,而一个村庄0～10岁的少年儿童的HBsAg阳性率为46%,说明在童年就已受到感染。e抗原测定的研究证实了该地区为高度流行区。从许多标本的阳性结果确证,在这些村庄中乙型肝炎的传播在典型的传播途径以外还有其它途径。在Lower Kalakag取牙龈拭子检查的25名儿童中有17名(68%)HBsAg血清阳性。这17名儿童中有15名的拭子漂洗液HBsAg也是阳性,未测出任何
In two remote Alaskan villages, hepatitis B virus (HBV) infection rates were as high as 55% by epidemiological and serological investigations. In adults, up to 55% of those with antibodies to hepatitis B surface antigen (HBsAg), while 46% of HBsAg-positive children in a village aged 0 to 10 years have been infected during childhood. Studies of e antigen assays confirmed the area as a highly endemic area. Positive results from many specimens confirm that there are other ways in which hepatitis B spread outside these typical routes of transmission in these villages. Seventeen (68%) of 25 children underwent gingival swab examinations in Lower Kalakag were HBsAg seropositive. Of these 17 children, 15 were positive for swab rinse liquid HBsAg, and none was detected