芳腈在温和条件下进行锆氢化反应,所得产物经水解得到芳醛;若经酰基化则得到N-酰基不饱和胺。后者不稳定,在室温下与甲醇发生加成反应得N-(α-甲氧基苄基)苯甲酰胺。过量的锆氢化试剂与芳腈反应,继之进行酰基化,得到二元酰基化产物,两个酰基分别加到腈基的碳与氮原子上。 The aromatic nitriles are subjected to zirconium hydride reaction under mild conditions, and the obtained products are hydrolyzed to obtain the aromatic aldehydes; if acylated, the N-acyl unsaturated amines are obtained. The latter is unstable and undergoes addition reaction with methanol at room temperature to give N- (α-methoxybenzyl) benzamide. Excess zirconium hydride reagent is reacted with the aromatic nitrile followed by acylation to give the dibasic acylated product, the two acyl groups being added to the carbon and nitrogen atoms of the nitrile group, respectively.