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目的:初步评价中医辨证治疗、中医辨证治疗加穴位贴敷、西药常规治疗三者对于哮喘轻中度发作风哮患者临床疗效。方法:将157例轻中度发作期哮喘患者随机分为3组,辨证组予中药颗粒剂麻苏止哮汤,综合组在辨证组基础上加用中药穴位贴敷,西药组按照哮喘指南口服西药,治疗10d。观察患者治疗前后中医症状积分、哮喘控制指标、嗜酸性粒细胞(EOS)的比值及实测值。结果:3种治疗方法均能显著改善中医症状积分、哮喘控制指标(P<0.01),辨证组白天症状改善优于其余两组(P<0.01),且辨证组可显著降低血清EOS的比值及实测值(P<0.01,P<0.05)。结论:3种治疗方案均能有效控制哮喘轻中度中医辨证风哮患者的急性发作,其中辨证组在白天症状控制上优于西药组及综合治疗组,且能降低血清EOS的比值及实测值。
OBJECTIVE: To evaluate the clinical efficacy of traditional Chinese medicine (TCM), syndrome differentiation of traditional Chinese medicine (TCM) plus acupoint sticking and traditional western medicine (TCM) on asthma with mild to moderate asthma. Methods: 157 mild to moderate asthmatic patients were randomly divided into three groups. The syndrome differentiation group was treated with granule of Susu Zhixiao decoction. The combination group was treated with traditional Chinese medicine acupoint sticking on the basis of syndrome differentiation group. The western medicine group was orally administered according to the asthma guidelines Western medicine, treatment 10d. Observed before and after treatment in patients with symptoms of Chinese medicine, asthma control indicators, eosinophils (EOS) ratio and the measured value. Results: All the three treatment methods could significantly improve symptom score and asthma control index (P <0.01). Syndrome differentiation improved significantly during the day than the other two groups (P <0.01), and syndrome differentiation group could significantly reduce the ratio of serum EOS and Measured value (P <0.01, P <0.05). CONCLUSION: All the three treatment regimens can effectively control acute exacerbation of mild and moderate asthma asthma patients. Syndrome Differentiation Group is superior to western medicine group and comprehensive treatment group in daytime symptom control, and can reduce the ratio of serum EOS and the measured value .