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目的:研究肝硬化患者院内感染的主要病原菌及药敏情况。方法:对解放军第302医院2005年12月到2008年12月有关肝硬化患者院内感染的临床资料进行回顾性分析。结果:1686例次院内感染革兰阴性菌为主,发生率最高为大肠埃希菌,约占所有菌株的31.8%,对多种抗生素耐药,其次为肺炎克雷伯菌,占12.3%;革兰阳性菌中表皮葡萄球菌占4.9%,金黄色葡萄球菌占4.0%;真菌中白色念珠菌最常见,占9.9%。结论:大肠埃希菌是肝硬化患者院内感染的主要病原菌,且对多种抗生素耐药。
Objective: To study the main pathogens and drug sensitivity of nosocomial infections in cirrhotic patients. Methods: A retrospective analysis was performed on the clinical data of nosocomial infection in patients with cirrhosis from the 302nd Hospital of PLA in December 2005 to December 2008. Results: Among the 1686 cases, Gram - negative bacteria was the most common in the hospital. The highest incidence was Escherichia coli, accounting for 31.8% of all isolates, resistant to many antibiotics, followed by Klebsiella pneumoniae, accounting for 12.3%. Gram-positive bacteria Staphylococcus epidermidis accounted for 4.9%, Staphylococcus aureus accounted for 4.0%; fungi Candida albicans most common, accounting for 9.9%. Conclusion: Escherichia coli is the main pathogen of nosocomial infection in cirrhotic patients and resistant to many antibiotics.