文献报道,缺血性脑血管疾病患者,血清高密度脂蛋白(HDL—C)的均值比正常对照组分别降低18%、20%和17%。而且男女两性均明显降低。Ford 研究颈动脉粥样硬化病变时,亦注意到这些病例的HDL—C 有所降低。由于血清HDL—C 浓度降低,使发生缺血性心脏病、缺血性脑梗塞以及短暂脑缺血发作(TIA)的危险性增加。这些观察研究认为,提高血清HDL—C 的浓度,可能延缓缺血性心、脑血管疾病的发生和发展。因此,积极地寻找能促使血清HDL—C 浓度升高的有效因素,对防治缺血性心、脑血管疾病有重要的临床意义。 Reported in the literature, in patients with ischemic cerebrovascular disease, mean serum HDL-C were 18%, 20% and 17% lower than the normal control group. And both men and women were significantly lower. When Ford studied carotid atherosclerosis, they also noted a decrease in HDL-C in these cases. The risk of developing ischemic heart disease, ischemic stroke, and transient ischemic attacks (TIA) is increased due to the reduced serum HDL-C concentration. These observations suggest that increasing the serum HDL-C concentration may delay the occurrence and development of ischemic heart and cerebrovascular diseases. Therefore, actively looking for an effective factor that can promote the increase of serum HDL-C has important clinical significance in the prevention and treatment of ischemic heart and cerebrovascular diseases.