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探讨高渗葡萄糖注入兔眼前房可能引起的损害。方法：分5组，每组5只眼抽出少量前房水后向前房注入50％或100％消毒葡萄糖溶液（G．S），15分钟后用生理盐水冲洗。第2组在注入50％G．S前向前房注入Healon0．2ml。第4组未冲洗前房。术后1，3，7天全麻下测眼压并照裂隙灯像，第7天眼滴锥蓝—茜素红染色后照角膜内皮细胞像并计数，部分角膜和眼球送电镜或光镜检查。结果：术后眼压变化及前房反应轻微，各组间角膜内皮细胞数无显著性差异（p＞0．05）光镜或电镜未见虹膜、房角或角膜内皮细胞的明显损害。结论：兔眼前房使用高渗葡萄糖引起的损害轻微，在Healon保护下使用可能更安全。
To investigate the possible damage caused by hypertonic glucose injection into the anterior chamber of rabbit eyes. Methods: Divided into 5 groups, 5 eyes of each group took out a small amount of aqueous humor and injected 50% or 100% sterile glucose solution into the anterior chamber (G.S). After 15 minutes, they were rinsed with saline. Group 2 injected 50% G. S Anterior chamber injection Healon0.2ml. Group 4 did not rinse the anterior chamber. Intraocular pressure was measured under general anesthesia at 1, 3, and 7 days after operation. The corneal endothelial cells were stained and counted on the 7th day after operation with eyedrops cone blue-alizarin red staining. Some corneal and eyeballs were examined by transmission electron microscopy or light microscopy . Results: There was no significant difference in intraocular pressure (IOP) and anterior chamber reaction between the two groups (p> 0.05). No significant changes were found in iris, angle or corneal endothelial cells under light or electron microscope. CONCLUSIONS: Hypodermic glucose damage in the anterior chamber of the rabbit eye is minimal, and it may be safer to use it under the protection of Healon.