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本研究主要目的为比较铋剂为基础的三联疗法与奥美拉唑为基础的三联疗法治疗Hp感染的治愈率和副作用。同时,随访1年以观察溃疡复发及Hp再感染的情况。 材料与方法:选择2年间141例复发的十二指肠溃疡并Hp阳性的患者作为研究对象。其中100例排除了M-R菌株(对甲硝唑耐药菌株),单盲随机分组;41例为M-R菌株,为非随机分组。治疗方法:(1)BTM方案:次硝酸铋75mg,qid,两餐间服;土霉素500mg,qid,进食时
The main purpose of this study was to compare the cure rates and side effects of bismuth-based triple therapy with omeprazole-based triple therapy in the treatment of Hp infection. At the same time, follow-up of 1 year to observe the recurrence of ulcer and Hp re-infection. MATERIALS AND METHODS: A total of 141 patients with recurrent duodenal ulcer and positive Hp in 2 years were selected as the study subjects. One hundred patients excluded the M-R strain (resistant to metronidazole) and were randomized in a single blinded manner; 41 were M-R strains and were not randomized. Treatment: (1) BTM program: bismuth subnutrition 75mg, qid, two meals between services; oxytetracycline 500mg, qid, eating