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目的探讨腹膜透析在重症急性胰腺炎救治中应用。方法采取腹膜透析治疗组46例,采取基础治疗对照组40例,观察两组患者的血淀粉酶恢复正常时间、死亡率等情况,并进行比较。结果腹膜透析治疗组46例中死亡5例,死亡率10.86%,基础治疗对照组40例中死亡12例,死亡率达30.00%;经统计学分析比较,差异有统计学意义(P<0.05)。结论膜腹透析在重症急性胰腺炎救治中应用可以有效的对循环中炎症介质进行清除,减轻全身炎症反应;可以将渗入腹腔的胰酶、炎症介质进行清除减少对胰腺及周围器官破坏;可以减轻胰腺水肿、促进肠麻痹恢复。
Objective To investigate the application of peritoneal dialysis in the treatment of severe acute pancreatitis. Methods 46 cases of peritoneal dialysis group were treated with 40 cases of basic treatment control group, and the blood amylase recovery time and mortality of the two groups were observed and compared. Results Peritoneal dialysis treatment group, 46 patients died in 5 cases, the mortality rate was 10.86%, basic treatment control group of 40 patients died in 12 cases, the mortality rate was 30.00%; by statistical analysis, the difference was statistically significant (P <0.05) . Conclusion Membrane dialysis in the treatment of severe acute pancreatitis can be effective in clearing the inflammatory mediators in the circulation, reduce the systemic inflammatory response; can penetrate the abdominal cavity of pancreatic enzymes, inflammatory mediators to reduce the destruction of the pancreas and surrounding organs; can reduce Pancreatic edema, promote intestinal paralysis recovery.