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目的根据抗缓激肽能抑制血管源性水肿的原理，探讨应用抗缓激肽药物Ｎｅｕｒｏｔｒｏｐｉｎ治疗大面积脑梗塞性脑水肿患者的可行性和有效性。方法选择５例年龄５５～８１岁，发病时间２４ｈ～６ｄ的大面积脑梗塞性脑水肿患者给予５％葡萄糖溶液５００ｍｌ中加入Ｎｅｕｒｏｔｒｏｐｉｎ３０ｍｌ静脉点滴，１次／ｄ，连续１０ｄ，跟踪脑ＣＴ及多伦多神经功能评分。结果４例病灶面积明显缩小，但病灶中心ＣＴ值无明显变化，其中２例神经功能明显改善。结论应用Ｎｅｕｒｏｔｒｏｐｉｎ为抗脑水肿治疗提供了一条新途径。
Objective According to the principle that anti-bradykinin can inhibit vasogenic edema, the feasibility and effectiveness of applying the anti-bradykinin drug Neurotropin in treating patients with cerebral infarction with cerebral edema were explored. Methods Five patients (55-51 years old) with cerebral infarction cerebral edema with onset time of 24h ~ 6d were randomly divided into 500ml of 5% dextrose solution and 30ml of Neurotropin intravenously once a day for 10 days. Function score. Results The area of 4 lesions was significantly reduced, but there was no significant change in the CT value of the lesion, of which 2 patients had significant improvement in neurological function. Conclusion The application of Neurotropin provides a new way for anti-brain edema treatment.