论文部分内容阅读
目的:探讨秋泻灵合剂与潘生丁联合治疗小儿秋季腹泻的临床疗效及安全性。方法:选取116例秋季腹泻患儿,随机分为对照组和治疗组,两组患儿均给与止泻、退热、调整电解质平衡等常规治疗,同时对照组给予潘生丁[5 mg/(kg·day),分2~3次口服]进行治疗,治疗组在此基础上加用秋泻灵合剂(5~10 mL/次,4次/日),两组均连续治疗3 d,观察两组患儿临床症状及体征改善情况及不良反应。结果:经治疗后,对照组总有效率为94.8%,治疗组总有效率为79.3%,治疗组总有效率明显高于对照组,具有显著性差异(P<0.05);治疗组各生理指标复常时间较对照组明显缩短,具有显著性差异(P<0.05);两组均未出现严重的不良反应。结论:秋泻灵合剂与潘生丁联合用于治疗小儿秋季腹泻,可明显改善患儿的生理指标,具有临床疗效较好,不良反应少等特点,具有一定的临床借鉴意义。
Objective: To investigate the clinical efficacy and safety of Qiu-Ling mixture and dipyridamole in the treatment of infantile autumn diarrhea. Methods: A total of 116 children with autumnal diarrhea were selected and randomly divided into control group and treatment group. Both groups were given routine treatment of diarrhea, antipyretics, electrolyte balance adjustment, while the control group was treated with dipyridamole [5 mg / (kg Day), 2 to 3 times orally]. The treatment group was treated with QZL (5 ~ 10 mL / time, 4 times / day) for two days. The two groups were treated for 3 consecutive days. Group clinical symptoms and signs of improvement and adverse reactions. Results: After treatment, the total effective rate of the control group was 94.8%, the total effective rate of the treatment group was 79.3%, the total effective rate of the treatment group was significantly higher than that of the control group, with significant difference (P <0.05) The recovery time was significantly shorter than that of the control group, with significant difference (P <0.05). No serious adverse reactions occurred in both groups. CONCLUSION: Qiu Xie Ling Mixture combined with dipyridamole can be used to treat infantile autumn diarrhea, which can significantly improve children’s physiological indexes. It has the characteristics of good clinical curative effect and few adverse reactions, and has certain clinical referential significance.