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目的 探讨病程超过 6小时的脑梗死动脉溶栓治疗的可行性。方法 44例脑梗死患者按病程分为A组 (病程≤ 6h)和B组 (病程 6~ 2 4h) ,两组均接受选择性动脉溶栓治疗。结果 对两组间的血管再通率、治疗前后神经功能缺损积分差值、病后 90天的巴氏指数、出血转化率和溶栓治疗中发生血管再通的时间进行比较 ,均无显著性差异。结论 部分脑梗死患者选择性动脉溶栓治疗时间窗可以延长至 6小时以后 ,且仍可以取得较高血管再通率和较好的临床疗效
Objective To investigate the feasibility of arterial thrombolysis in patients with cerebral infarction over 6 hours. Methods According to the course of disease, 44 patients with cerebral infarction were divided into group A (duration ≤ 6h) and group B (duration 6 ~ 24h). Both groups received selective arterial thrombolysis. Results There was no significant difference between the two groups in the rate of recanalization, difference in neurological deficit scores before and after treatment, the Papanicola of 90 days after illness, the rate of hemorrhage conversion and the time of recanalization during thrombolytic therapy difference. Conclusions The time window of selective arterial thrombolysis in patients with partial cerebral infarction can be extended to 6 hours later, and the high recanalization rate and better clinical efficacy can still be achieved