Balo病(同心圆硬化症)是一种中枢神经脱髓鞘疾病,特征性的病理改变为病灶内脱髓鞘层与髓鞘保留层成同心园状排列。本病的诊断一直是依据病理学检查。近年来,由于MRI能显示同心园层病变,使本病有可能根据临床症状和MRI表现作出临床诊断。本文综合Balo病的临床表现,诊断及治疗报告如下。 临床表现:约半数病例有低热、倦怠、恶心、头痛等前驱症状,初期多为意识、精神、言语、运动、行走等方面障碍,大约1～3周达高峰期。重症则出现去大脑强直、去皮质状态、完全性失语、痉挛性四瘫、大小便失禁等大脑症状。脑膜刺激征和痉挛少 Balo’s disease (concentric sclerosis) is a demyelinating disease of the central nervous system characterized by a concentric, park-like arrangement of the demyelinated layer in the lesion and the myelin retention layer. The diagnosis of the disease has always been based on pathological examination. In recent years, MRI can show concentric park lesions, so that the disease may be based on clinical symptoms and MRI findings to make a clinical diagnosis. This article summarizes the clinical manifestations of Balo disease, diagnosis and treatment report is as follows. Clinical manifestations: about half of the cases have low fever, fatigue, nausea, headache and other prodromal symptoms, initially more awareness, spirit, speech, exercise, walking and other obstacles, about 1 to 3 weeks reached its peak. Severe cases appear to brain rigidity, cortex status, complete aphasia, spastic quadriplegia, incontinence and other brain symptoms. Meningeal irritation and spasms less