论文部分内容阅读
目的分析注意缺陷多动障碍(ADHD)儿童的血液微量元素与社会功能的相关性,从营养学角度为改善ADHD患儿的社会功能缺陷提供科学依据。方法应用Weiss’s功能性缺陷程度评定量表(WFIRS-P)对144名ADHD儿童社会功能进行评价,检测血液铜、锌、钙、镁、铁、磷、铅的浓度,并计算铜/锌比值,然后对WFIRS-P量表评分与各微量元素水平进行相关的统计学分析。结果经t检验分析,ADHD患儿血清锌离子(P<0.05)、镁离子(P<0.01)明显低于正常对照组,两组间的其余各元素及铜/锌比值差异均无统计学意义(P>0.05)。经多元线性逐步回归分析,发现血清铁的浓度变化与患儿的冒险活动具有相关性(P<0.05),其余元素与ADHD儿童的家庭、学习和学校、生活技能、自我观念、社会活动等社会功能之间未发现显著的相关性。结论锌、镁元素可能是ADHD儿童的保护因子,铁元素对ADHD儿童的冒险活动具有影响,微量元素的失衡将对ADHD儿童的社会功能造成损害。
Objective To analyze the correlation between blood trace elements and social function in children with attention-deficit hyperactivity disorder (ADHD) and provide scientific basis for improving social function defects in children with ADHD. Methods The social function of 144 children with ADHD was assessed by Weiss’s Functional Defect Rating Scale (WFIRS-P). The concentrations of copper, zinc, calcium, magnesium, iron, phosphorus and lead were measured and the copper / zinc ratio was calculated. Then the correlation between WFIRS-P scale and each trace element level was statistically analyzed. Results There was no significant difference in serum Zn (superscript +) and magnesium (P <0.01) between children with ADHD and normal controls (P> 0.05). After multiple linear stepwise regression analysis, it was found that serum iron concentrations were correlated with adventurous activities in children (P <0.05). The rest of the factors were related to ADHD children’s family, learning and school, life skills, self-concept and social activities No significant correlation was found between the functions. Conclusion Zinc and magnesium may be protective factors for children with ADHD. Iron may have an impact on adventurous activities of children with ADHD. The imbalance of trace elements will impair the social function of ADHD children.