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为了研究消化系肿瘤患者围手术期的免疫状态，应用流式细胞仪对８０例消化系统瘤患者手术前后Ｔ细胞表面３种细胞表型进行了监测，并与良性病变患者进行了对比分析。发现消化系肿瘤患者术前低于对照组（Ｐ＜０．０５），ＣＤ３＋／ＨＬＡ－ＤＲ＋与对照组相同；术后ＣＤ１６、ＣＤ６９、ＣＤ３＋／ＨＬＡ－ＤＲ＋均增高（Ｐ＜０．０５），活化Ｔ细胞ＣＤ３＋／ＨＬＡ－ＤＲ＋明显高于对照组（Ｐ＜０．０１）。提示消化系肿瘤患者术前免疫功能低下，术后活化Ｔ细胞明显增多，表明切除肿瘤有益于增强机体抗瘤能力，提高患者的免疫功能活性，说明减瘤手术是必要的
In order to study the perioperative immune status of patients with digestive tumors, flow cytometry was used to monitor the three cell phenotypes of 80 patients with digestive system tumor before and after surgery, and compared with benign lesions. The patients with digestive neoplasms were found to be lower than the control group before surgery (P<0.05), and the CD3+/HLA-DR+ levels were the same as those in the control group; the levels of CD16, CD69, and CD3+/HLA-DR+ were all increased (P<0.05). The activated T cells CD3+/HLA-DR+ were significantly higher than those in the control group (P<0.01). The preoperative immune function in patients with digestive cancer is low, and the number of activated T cells after surgery is significantly increased, indicating that the removal of tumors is beneficial to enhance the body’s anti-tumor ability and improve the patient’s immune function activity, indicating that tumor reduction surgery is necessary.