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Tuberculosis,historically one of the deadliest and most prevalent infectious diseases,is caused by the bacterium Mycobacterium tuberculosis.It is estimated that one-third of the worlds population is infected by this agent (Zumla et al.,2014),and tuberculosis is therefore a major topic for medical students.M.tuberculosis is a small aerobic bacillus,with a remarkably high lipid-content cell wall that plays a critical role in its pathogenicity.